ABSTRACT
An increasing incidence of rhinoorbitocerebral mucormycosis (ROCM) among patients with COVID-19 has recently been reported in India. We report the imaging findings for 25 patients with COVID-19 and invasive ROCM at a single hospital in India. Findings included sinus wall erosions (n = 20), air within bony sinus structures (n = 11), and focal mucosal nonenhancement (n = 8). Orbital, vascular, and intracranial complications were also observed. Radiologists should recognize the increasing incidence of ROCM among patients with COVID-19 to facilitate early diagnosis.
Subject(s)
COVID-19/complications , Central Nervous System Fungal Infections/diagnostic imaging , Mucormycosis/diagnostic imaging , Orbital Diseases/diagnostic imaging , Paranasal Sinus Diseases/diagnostic imaging , Adult , Aged , Central Nervous System Fungal Infections/epidemiology , Central Nervous System Fungal Infections/microbiology , Female , Humans , Incidence , India/epidemiology , Magnetic Resonance Imaging/methods , Male , Middle Aged , Mucormycosis/epidemiology , Optic Nerve Diseases/diagnostic imaging , Optic Nerve Diseases/microbiology , Orbital Diseases/epidemiology , Orbital Diseases/microbiology , Paranasal Sinus Diseases/epidemiology , Paranasal Sinus Diseases/microbiology , Paranasal Sinuses/diagnostic imaging , Paranasal Sinuses/microbiology , Retrospective Studies , Tomography, X-Ray Computed/methodsABSTRACT
Coronavirus disease (COVID-19), caused by a highly contagious novel coronavirus, has seen a rapid surge of cases over the past 6 months spreading to more than 215 countries and posing a global threat to mankind. Reverse transcriptase-polymerase chain reaction (RT-PCR) from pharyngeal swabs is considered the gold standard for diagnosis of this disease. Portable chest radiography (CXR), point of care ultrasound, and computed tomography (CT) are crucial modalities in diagnosis and follow-up. Portable CXR can help in patients who are clinically unstable, and also to prevent the cumbersome process of steriliastion after every CT scan. However, chest CT is useful as a problem-solving tool, to look for progression and complications associated with the disease. In a few cases, in our experience (as has also been documented by others), RT-PCR was negative in early disease, and CT chest was able to detect the radiologi-cal findings raising suspicion of COVID-19. With this pictorial review, we aim to describe and illustrate the typical, and a few atypical, radiological findings of this disease.